Teams

The team develops several research topics, combining neuroscience, physics and chemistry in order to unravel the dynamics and nanoscale organization of multimolecular receptor complexes and their functional role in glutamatergic synaptic transmission in health and disease. Recently, the team has engaged in a major program to analyze and understand the interplay between AMPA type glutamate receptor nanoscale dynamics, synaptic plasticity and memory formation in the healthy and diseased brain. Our latest developments are a major thrust in combining molecular and physiological studies as well as analyzing neurodevelopmental disorders related to synapse dysfunction.

• Research focus 1 : Dynamics and physical-chemistry of the macro-molecular complexes of the synapse
• Research focus 2 : Nano-scale organization and dynamics of synaptic proteins and membrane trafficking
• Research focus 3 : Impact of the dynamic of synapse organization on synaptic physiology
• Research focus 4 : Mechanism of synapse and brain dysfunction in neurodevelopmental diseases such as autism spectrum disorder and mental retardation